Looking for this by disease rather than by figure? See the IMD disease hub — 1,064 IMDs with causal gene, VMH/WBM coverage, biomarkers and ICIMD group.
Source book:
Every disease chapter of Saudubray's Inborn Metabolic Diseases (5th ed.) opens with a pathway diagram. Each diagram was audited reaction-by-reaction against the VMH human reconstructions and the whole-body models (WBMs), the genuine gaps were triaged, and a set of curation and WBM additions were built. This page summarises that work and shows a “reconDBdelta version” of every chapter figure — each arrow labelled with the reconDBdelta reaction used.
609
Reactions audited
38 chapters (6–43)
544
In a human recon
89%
521
In the WBMs
86%
59
Gaps
no VMH reaction
6
Microbe-only
not a human gap
10
Migrations
041–079
Coverage status of audited reactions
Click a bar or a chip to list those reactions (formula, GPR, subsystem). Re-audited against the current reconDBdelta (2026-07-14, upgrade-only).
Use +/− (or Ctrl/⌘ + scroll) to zoom; scroll to pan. Vector figure stays sharp at any zoom.
Notes & provenance
Figure layout is auto-generated (layered by pathway depth) — it approximates, not reproduces, the book's drawn topology.
Status re-audited against the current reconDBdelta (upgrade-only); reactions added this campaign show as “in WBM” (RE2493C, BAAT4x, GSNKm, HMR_0808; SERR now in recon).
Source: Saudubray, Inborn Metabolic Diseases (5th ed.). Reaction-anchored audit. Curator CC, 2026-07-14. All database changes are on the local reconDBdelta until run on the server.
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