Curation area
Tools for curators to correct and improve the VMH knowledge base — reaction balancing, metabolite structures, subsystems, GPRs, and reconstruction ingestion.
These tools require a curator/editor role; you'll be asked to sign in if needed.
Overview
Tools
Reaction mass & charge balance
Find mass/charge-imbalanced reactions, inspect each metabolite's formula & charge, edit or upload a corrected .mol structure, and auto-recompute the metabolite's properties. Atom mapping (RDT) per reaction.
Metabolites missing a structure
Worklist of metabolites with no .mol file in /ctf. Draw (seeded from SMILES) or upload a structure; saving recomputes the metabolite's properties.
Subsystem review & curation
Browse every subsystem with its reaction count; open one to see its reactions (with formula) and move any reaction to another subsystem (existing name or new).
GPR review & curation
Review gene-protein-reaction rules for the human Recon4D models with each gene symbol validated against the HGNC catalogue (unknown symbols flagged); edit the GPR and set its curation status (not curated / manually curated / curator approved / unknown (curated)).
Molecule / structure editor
Draw, edit and save metabolite structures into the shared mol-file library (Ketcher).
Master-file upload
Upload a WBM reconstruction master-file (.xlsx) to ingest reactions/metabolites into a target model.